Microflora of chronic humeral osteomyelitis

Purpose. To reveal the pathogens of humeral osteomyelitis in patients with different mechanisms of the disease. Materials and Methods. Sampling of patients with humeral osteomyelitis treated at “RISC RTO” within 1969-2013 performed. Patients (n = 212) divided into groups depending on the forms and mechanism of the disease development. Pathogens of the infection process analyzed in 63 patients. Bacteria identification and antibiotic sensitivity procedures performed by traditional methods using «WalkAway 40» bacteriologic analyzer. The frequency of pathogen occurrence expressed as percentage of the total number of strains of the bacteria isolated. Results. Chronic humeral osteomyelitis has been established to develop most often (in 51 % of cases) after treatment of closed fractures. Microcenosis in examined patients varied depending on the type and mechanism of osteomyelitis development. Conclusion. The use of antibacterial preparations in patients with chronic humeral osteomyelitis should be carried out in view of microcenosis determining the inflammatory process, and oriented towards S.aureus monoculture (patients with hematogenous osteomyelitis and osteomyelitis developed in the process of treating open fractures), or towards bacterial associations with P. aeruginosa, E. coli, P. mirabilis, S. marcescens, A. faecalis gram-negative bacteria (in patients with gun-shot osteomyelitis and osteomyelitis after treating closed fractures).