Modern concepts of negative disorders in schizophrenia and schizophrenic spectrum diseases

To date, there is a widespread perception of schizophrenia and schizophrenic spectrum disorders as predominantly progressive diseases with an unfavorable prognosis. The possibility of a regredient course of schizophrenia up to a complete stop of the pathological process was noted by the classics of psychiatry. Thus, E. KgaereIp described periods of weakening and even complete disappearance of psychopathological symptoms, he also used the concept of "social recovery" for the first time in schizophrenic spectrum diseases. E.B1ei1eg also allowed the "stopping" of the schizophrenic process, and at any stage of the disease, believing that various variants of the course, outcome and prognosis of schizophrenia are possible. K.Schneider described patients with prolonged spontaneous remissions after a single expanded schizophrenic attack, and the duration of remissions reached 50 years, and patients at the same time maintained a good level of social adaptation.