Molecular genetic abnormalities of PIP5K2A regulation in schizophrenia and depression

This paper presents the current data of literature and our own results of an extensive research on the role of molec-ular genetic disturbances of phosphatidylinositol-4-phosphate 5-kinase type 2 alpha (PIP5K2A) neuronal signaling pathways in the pathophysiological processes in the main socially important psychiatric disorders. Particular attention is paid to identifying the various associations of polymorphic variants PIP5K2A gene with schizophrenia, tardive dyskinesia, and depression.