Molecular markers of hemostasis system after total large joint endoprosthetics through antithrombotic prevetion with heparin of low molecular weight

The analysis of hemostasis indices was performed in 83 patients that had major joint arthroplasty. It showed that using molecular markers enabled to reveal preoperative coagulation and fibrinolysis dysfunction, to investigate the dynamics of hypercoagulation syndrome phase changes, to trace the intensity and variability of thrombinemia by standard antithrombotic prophylaxis with enoxaparin.