Molecular analisys of VEGF family gene expression in bone marrow mononuclear cells after pletting

In the treatment of ischemic myocardial lesions are widely used mononuclear cells of autologous bone marrow. In the study of molecular-biological characteristics of human cells among the fractions of adherent and non-adherent bone marrow mononuclear cells, we have shown marked differences in the level of mRNA expression of genes vasoendotelial growth factor-A,-B,-C and-D. In adherent cells prevails expression of mRNA genes VEGF-C and VEGF-B. While in non-adherent mononuclearas it was increased mRNA expression of genes VEGF-D and-B, to a lesser extent - VEGF-A It describes the fundamental differences of biological properties of these fractions.