Morph functional changes of ferments in the neutrophiliac of peripheral blood in the case of virus hepatitisn “B” at children

The activity of SDG, LDG, G-6-FDG and α-GFDG at ill children has been studiet. The change of ferments activing in depending of VHB course heaviness has been investigated. Steady and deep lowering of dehydrogenises activing was marked at 6 patients (6,8 %) with fulminant form of VHB. It was concluded that at VHB the aerobic way of carbohydrate transformation (SDG) is sharply disordered α-glycerol phosphate (α-GFDG) and peptone phosphate (G-6-FDG) bypasses are suffered, as well as glycolysis (LDG) is activated. It is evidence of acute changes in energy phenomena, leading to the gathering of lactate and metabolic acidosis. Steady lowering of dehydro genesis is prognostically unfavorable indicator of VHB course.