The morphological picture of the estrous cycle at the reserpine model at the depression in rats

In a study on rats in the evaluation of morphological picture of vaginal smears studied the effect of reserpine model of depression in the course of the estrous cycle. The action of reserpine at a dose causes prolongation depress estrous phase, decrease in estrus squamous cell and decrease karyopyknotic index. It is concluded that the depletion of stocks of reserpine-catecholamine neurotransmitters violates neuroendocrine mechanisms controlling reproductive function and leads to the development hypoestrogenic state.