Morphological assessment of the systemic impact of titanium and hafnium nitride coated implants on experimental animals and their offspring

The material of morphological study of the effect of transosseous implants made of 12X18H9T steel coated with NHf+TiN on the parenchymatous organs and heart of the experimental rat offspring is presented. Analysis of the obtained results showed the safety of the long-term presence of the implants in the bone tissue and the negative impact of metal ions on the developing embryos. Morphological study of a number of rat organs in the postnatal period had an intact histological structure without gross destructive and necrotic changes.