Morphological methods for diagnosing breast cancer in cats

Morphological research allows differentiating mammary gland neoplasms from other tumors simi-lar in localization, to define the type and stage, ma-lignancy degree and also some other features al-lowing making full oncological diagnosis. The work purpose was to define informational content of cyto-logical method in diagnosis of breast cancer (BC) in cats and to reveal most widespread BC histological type in cats in the region. As material for the re-search the cats of different breeds and age groups with spontaneously arisen new growths of mamma-ry gland served. Clinical supervision and microsco-py were carried out in veterinary clinic of the Center of Beauty and Health of Animals "Zoostyle" (Volgo-grad) and at the Chair of Morphology, Pathology of Animals and Biology of FSBEI HE "Saratov SAU". By the results of the researches breast cancer was diagnosed in 271 animals (89.1 %): cats females - 269 (99.3 %) and cats - 2 (0.7 %). In 99.2 % of cases mammary gland carcinoma and only in 0.8 % - carcinosarcoma was diagnosed. In most cases (94.4 %) at cytomorphological diagnostics of BC the carcinomas of nonspecific type having general cytological signs of malignancy were diagnosed. The results of cytological researches convincingly prove that in view of violations of intercellular con-nections it is noted mainly abundant cytosis. Poly-morphism is characterized by a variety of forms and sizes of cells and kernels, unevenness of chromatin distribution, unevenness and fuzziness of nuclear membrane contours, improper cell placement. At histological research of operational material, de-pending on morphological type, adenocarcinoma (generally simple tubular-papillary type) in 77.8 % of cases; solid carcinoma - 20.8, squamous and anaplastic carcinoma - 1.4 % were allocated. De-pending on BC morphological type in cats in the city of Volgograd tubular-papillary adenocarcinoma of simple type has the widest circulation. The re-sults of histological research allow making full on-cological diagnosis taking into account detailed morphological characteristic of new growth struc-ture that will help to define further tactics of most reasonable treatment of animal patient.