Morphological appearance of lung alterations in 14-day experimental model of West Nile fever on mice

Structural injuries of respiratory parts of the lungs were revealed in a 14-day experimental model West Nile fever on mice. These morphological changes are preserved despite the reduction of neurologic signs. The data obtained by us, apparently, indicate tropism of the used strain (Astr 901) to the endothelium of capillaries of interalveolar septa, and persistence of the virus in epithelial cells of alveoli and alveolar macrophages.