Morphologic variants of Castleman’s disease and density of vascular net in tissue of lymph nodes

Vascular density was studied in the lymph node biopsies from 28 patients with Castleman’s disease (hyaline vascular and plasma cell types) with the help of digital histomorphometry. The method allowed for quantitative assessments and statistical analysis. Plasma cell type demonstrated the highest vascular density. The data on hyaline vascular Castleman’s disease showed a high statistical spread, suggesting heterogeneity of this particular type of the disease.