Intravenous infusion of albumin in a multidisciplinary clinic

Rationale: Albumin is one of the most important proteins, playing a significant role in maintaining colloid osmotic pressure, wound healing, reducing oxidative damage, transport of drugs and endogenous substances, and coagulation.Objective: To identify patterns of albumin infusions in a multidisciplinary hospital, to assess the compliance of albumin use with the standards of medical care.Methods: Retrospectively, based on materials from 43,710 electronic medical records, the infusion of albumin solution to hospital patients at the Pirogov Center in 2023 was studied. Infusions of 25% albumin solution in 50 ml bottles (Kedrion, Italy) were performed. The data were studied using descriptive and inductive statistics, analysis of variance ANOVA at a significance level of 0.05.Results: 146 people (0.3%) received albumin infusions. In total, patients received 2466 vials of albumin, or an average of approximately 211 grams of albumin per patient. There were 5 groups of albumin recipients: 1) cardiac surgery (n = 45); 2) oncohematology (n = 14); 3) oncology (n = 35); 4) trauma/orthopedics (n = 16); 5) other (n = 36). There were no gender differences in albumin recipients in terms of age, duration of treatment, mortality, volume or regimen of albumin administration. In the selected groups of patients, significant differences in age were revealed. Minimum age - in the oncohematology group: median (quartiles) - 43 (35; 52) years, maximum age - in the oncology group: 67 (59; 73) years (p function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }