Some peculiarities of pathomorphosis of schizophrenia (according to data of epidemiological investigation)

Comparative clinical-catamnestic investigation of all patients diagnosed with schizophrenia being under therapy at the twenty-four-hour institution Yu. K. Erdman KSIH Altai Krai Clinical Mental Hospital in 1987 (N=503) and 2007 (n=732) has been carried out. For indicated time interval, significant change of social adaptation of patients has been revealed that is testified by increase (as much as 1,7 times) of portion of disabled persons and number of incapacitated persons (as much as 9 times). Change of clinical dynamic characteristic of the schizophrenic process has been noted: increase (from 4,64 % in 1987 to 20,29 % in 2007) of specific weight of psychopath-like symptoms in clinic of paranoid schizophrenia and associated with this growth (as much as 1,5 times) of number of repeated hospitalizations of patients in psychiatric institution as well as increase of prevalence of co-morbidity of schizophrenia with chemical addictions.