A new method for diagnosing proliferative vitreoretinopathy

The objective of the study: to study a standardized model of a gunshot penetrating wound of the eye without an intraocular foreign body (type B open globe injury). Materials and methods. The experimental study was performed using a standardized model [1] of 36 Chinchilla rabbits (71 eyes). A gunshot penetrating wound to the eye without an intraocular foreign body, an open type B globe injury (OGI B), was simulated using an air rifle and upgraded projectiles for it. After modeling OGI B, a detailed ophthalmological analysis of the animals was performed on the control days of the study. A set of modern standard and high-tech methods for determining proliferative vitreoretinopathy (PVR) were used: ophthalmoscopy, optical coherence tomography (OCT), magnetic resonance imaging (MRI), ultrasound (USG) and histological examination of the eyeball. Nonparametric statistical methods were used. Results. An analysis of the information content, including comparative analysis, of the used methods for diagnosing PVR proved the relevance of each of them. Additionally, the use of MRI has demonstrated for the first time a high level of information and visibility in the diagnosis of ARV. Conclusion. The study of proliferative signs using various methods of analysis (histological, ophthalmoscopy, OCT, USG and MRI) confirmed the possibility of their use as markers of PVR. It also made it possible to replace these diagnostic methods in the diagnosis of proliferative changes after injury. MRI as a method of diagnosing PVR is noted for its high information content and visibility.