Prospects for the use of direct renin inhibitor aliskiren for the treatment of socially significant diseases

This review analyzes the results of randomized studies of the efficacy and safety of direct renin inhibitor aliskiren in the treatment of patients with arterial hypertension associated with obesity, diabetes, menopause, kidney failure, chronic kidney disease, and metabolic syndrome. The authors conclude that, along with the hypotensive action, aliskiren exerts cardioprotective and renoprotective effects that can expand the indications for the use of this drug.