The extent of liver involvement and results of cy to reductive surgeries in colorectal cancer patients with simultaneous liver metastases

A total of 364 patients with colorectal cancer and simultaneous liver metastases were treated at the Medical Radiology Research Center from 1977 to 2003 and at Kaluga Oncology Clinic from 1994 to 2003. The analysis of treatment results and their dependence on the extent of hepatic parenchyma involvement was carried out. Cytoredictive surgeries for liver involvement up to 25 % and 50 % resulted in increase in life span of the patients respectively up to 21,0 and 17,0 months. Metastases into lymph nodes with liver involvement to 25 % made the prognosis worse but excluded no feasibility of performing cytoredictive surgery. Cytoreductive surgery was not advisable if the hepatic parenchyma involvement was more than 50 %.