The pyeloureteral junction obstruction: etiology, pathogenesis, morphological features

Introduction. Congenital anomalies of the kidneys and urinary tract cause chronic kidney disease in 7% of cases. The zone of the pyeloureteral segment (PUS) is affected most often. The kidney and ureter originate from two different rudiments, the violation of their connection under the influence of teratogenic or genetically determined causes determines the obstruction of the pelvic-ureteral junction.