Review of the methods of genetic differentiation of pseudotuberculosis pathogen strains

Pseudotuberculosis is an infectious disease, the causative agent of which is Yersinia pseudotuberculosis. The disease appears in the form of sporadic outbreaks and causes significant damage to the health of the population. In addition to timely detection of the pathogen, various methods are used to effectively determine whether the pathogen belongs to a particular strain. Currently, various methods are used for genotyping strains of the causative agent of pseudotuberculosis. The review presents the methods of genetic differentiation most frequently used in recent years: MLVA, MLST, IS-RFLP, etc. The analysis of the applied methods will help to choose the most effective method for genotyping the causative agent of pseudotuberculosis, as well as to choose the vector of development of a new approach.