Assessment of antitoxic and anti-infectious actions of the experimental preparation

In the course of the research, the antitoxic and anti-infectious effects of the developed drug were determined on white mice and white rats. To assess the antitoxic effect in the experiment on white rats, cadmium damage was modeled, followed by taking into account the antidote activity. An increase in the survival rate of animals receiving the drug was found - 60 % versus 40 % in the control, higher hematological indicators: the content of hemoglobin, erythrocytes and leukocytes in the blood of experimental animals was higher than similar control values, respectively, by 3.8, 15.3 and 16,4 %. The anti-infectious effect of the feed additive was determined during the experiment on infecting white mice with the causative agent of Escherichiosis - E. coli (strain "KB-1"). It was found that the introduction of the study drug into the diet of infected animals smoothed the clinical picture of the infectious process, had a hemoprotective effect: the content of erythrocytes, leukocytes, neutrophils, lymphocytes, neutrophils in the blood of experimental animals exceeded the control values, respectively, by 2.5, 13.6, 16, 7, 14.3, 28.6 %. The results of the investigated subject showed that the investigational drug has a well-pronounced antitoxic and anti-infectious effect.