Evaluation of the efficacy and tolerability of combination therapy for lower urinary tract symptoms in patients with chronic prostatitis and benign prostatic hyperplasia

Introduction. Chronic prostatitis (CP) is one of the most common urological diseases; CP often accompanies benign prostatic hyperplasia (BPH). Quite often in patients with CP, obstructive, irritative and urethral symptoms are detected. However, there is simply no effective therapy for CP. Despite the lack of data on the proven effectiveness of herbal medicine in international clinical trials, this treatment for CP and BPH remains popular. Aim. To study clinical efficacy and safety of CHINCH herbal drug in treatment of patients with CP and BPH. Materials and methods. 820 men from 13 clinical centers of the Russian Federation with lower urinary tract symptoms associated with CP and BPH were included in the study. The patients were divided into 2 groups. Group I included 423 patients who were administered a complex therapy with Tamsulosin (0.4 mg, 1 capsule once a day for 2 months) and CHINCH (2 capsules 2 times a day for 2 months). Group II consisted of397patients who had only Tamsulosin (0.4 mg, 1 capsule once a day for 2 months). Results. According to uroflowmetry, the patients from the group with combined therapy showed significantly better average values of the maximum urine flow rate (Qmax) at the end of 2 months of the therapy, than the initial values in the group, as well as the values of the monotherapy group (p function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }