Evaluation of the effectiveness of preventive effect of bread with extract of brown seaweed

The study presents the results of researching hepa-toprotective and antioxidant action of bread with the addition of a new ingredient - water-ethanolic extract of brown algae Fucus evanescens, on the model of toxic hepatitis in experimental animals. The object of the study was the bread from wheat flour with the addition of water-ethanolic extract of brown algae Fucus eva-nescens. In the study experimental model of toxic hepa-titis in animals (rats), by intoxication with one of strong stimulators of lipid peroxidation (LP) - carbon tetrachlo-ride was used. The evaluation of integral antiradical activity (IAA) of antioxidants was carried out by their ability to suppress the oxidation of ABTS by peroxyl and alkoxyl radicals. The index of IAA was determined in hepatocytes of the liver, using the spectrophotometer in which the change in extinction was recorded. In the rats receiving bread with seaweed extract, there was a ten-dency to reduce relative weight of the liver, which testi-fies to its protective role in the composition of the prod-uct...