Evaluation of the effectiveness of nonoperative management of abdominal organ with spontaneously stopped internal bleeding in a model of combined radiation injury

Автор: Kraynyukov P.E., Zhabin A.V., Nosov A.M., Seleznev A.B., Samokhvalov I.M., Pichugin A.A.

Журнал: Московский хирургический журнал @mossj

Рубрика: Экспериментальные исследования

Статья в выпуске: 4 (82), 2022 года.

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Introduction. The results of the research conducted in the 80s of the twentieth century allowed us to formulate the basic principles of surgical treatment of combined radiation-mechanical lesions (CRMP), however, the possibilities of new therapeutic technologies developed in recent decades in relation to CRMP have not been sufficiently studied. The tactic of non-surgical treatment (NOL) of abdominal injuries with stopped internal bleeding is increasingly used for abdominal injuries, however, we have not found reports of the use of this tactic in CRMP in the available literature.The aim of the study was to conduct a comparative experimental assessment of the effectiveness of the tactics of NOL and laparotomy in abdominal injuries with stopped intra-abdominal bleeding as a component of CRMP.Materials and methods. The study was conducted on 41 rabbits of the Soviet Chinchilla breed, males weighing 2,5-3,0 kg. Rabbits were randomly divided into 5 groups depending on the experimental conditions.The results of the study. The choice of the method of surgical treatment of abdominal injuries with stopped internal bleeding - NOL or laparotomy, modifies the nature of the course of PKK, but not its outcome. It was found that the NOL tactic does not cause the death of animals in the early period of modeling the mechanical component of the CRMP, since it is not accompanied by additional trauma and additional intraoperative blood loss.Conclusion. The results obtained allow us to assert that the choice of tactics for NOL injuries of abdominal organs with stopped internal bleeding in CRMP in the experiment contributes to a more favorable flow of radiation and mechanical components compared with the results of the classical approach with surgical removal of abdominal injuries.

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Combined radiation injury, intra-abdominal bleeding, non-operative management

Короткий адрес: https://sciup.org/142236454

IDR: 142236454   |   DOI: 10.17238/2072-3180-2022-4-61-69

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