Assessment of the general toxicity of animal feed of Sterlitamak district of the Republic of Bashkortostan

The results of the toxicological study of feed received from some farms in the Sterlitamak district of the Republic of Bashkortostan (Kalinin AP LLC; Avangard LLC; Salavat Agrofirm LLC) are presented. In the studied feeds, the overall toxicity was determined according to GOST 316742012 on 3 types of test objects (white mice, stilonychia, rabbits). Most of the feeds submitted for the study of biotesting on the stylonychies were benign, weak toxicity was detected in 5.88% of the samples (experiment on the simplest). Postmortem examination of the internal organs of white mice (after intragastric administration of the feed extract) showed no visible morphological changes. Not identified dermatonecrotic action when applying extracts of feed on the skin of rabbits. Consequently, most of the feed was conditionally benign (according to the results of this test), 5.88% of low-toxic samples are not recommended for feeding. At the same time, the results of the study revealed the fact that the official interpretation of the results requires adjustment depending on the type of animal. For example, in the case of toxicity on stylonychia (primary screening) and the absence of toxicity in mice and rabbits (basic methods), the food is officially considered nontoxic, but given that the microflora of the rumen, including infusoria, plays a special role in digestion be considered toxic.