Evaluation of prebiotic activity of plant extracts towards development of preparations stimulating intestinal microflora

The investigation was aimed at evaluation of prebiotic activity of both high and low doses of aqueous medicinal plant extracts, green and black tea. Ability to retain biofilm formation and bacterial survival in mature sessile cultures of Escherichia coli BW25113 was measured during incubation in a fresh medium supplied with different doses of extracts. Both high and low doses of Arctostaphylos uva-ursi, Vaccinium vitis-idaea, green and black tea induced biofilm formation but had vаrious effects on bacterial survival. The highest prebiotic activity was observed in low doses of A. uva-ursi and V. vitis-idaea, and in high doses of green tea as well. The extracts of Betula pendula and Laminaria japonica did not affect biofilm formation but demonstrated moderate bactericidal activity.