The evaluation of wound healing effect of the extract of black leaves of Bergenia crassifolia during experimental thermal burn

Morphological features of the healing of burn wounds by application of the extract of black leaves of Bergenia crassifolia were studied in the research. The experiment was carried out on mongrel white rats weighing 180-200 g on the model of experimental thermal burn. The analysis of the reparation of the wound surface was carried out on 6, 13 and 20-th day since the injury. Laboratory animals used in the experiment were divided into three groups based on gender, age, weight and randomization principle. In control group of untreated animals, severe hyperemia with coagulation necrosis, penetration of purulent exudate into the deep layers of the skin, characterized by a greater thickness of the leukocyte-necrotic scab and a lower height of granulation tissue, was revealed. It was found that under the influence of the extract of black leaves of Bergenia crassifolia healing proceeded more intensively than in the control, which is expressed by a smaller thickness of the leukocyte-necrotic scab, accelerated epithelialization and complete closure of the skin defect...