Assessment of influence on endothelial function of beta-adrenoceptor blocking agent of nebivolol and negative catalyst of angiotensine transforming enzyme of quinapril in the patients with arterial hypertension

Vascular endothelium plays an important role in regulating such processes as dilation and constriction of vessels, adhesion of platelets and growth of smooth muscular cells in vessels. This article is devoted to the research of the endothelial function of betaadrenoceptor blocking agent of Nebivolol and negative catalyst of angiotensine transforming enzyme of Quinapril and their influence on the patients with arterial hypertension in randomised open-label study. The assessment of influence of these medicines was based onphysical examination data, measurement of blood pressure, endotheliumdependent vasodilation and endothelium-independent vasodilation under ultrasound investigation of brachial artery. It has been found out that antihypertensive therapy with these medications normalizes defective endothelium-dependent and endotheliumindependent functions of resistance vessels.