Evaluation of the effect of the drug "Antavit" on blood biochemical parameters in experimental hepatitis of rabbits

The aim of the research was to study the effect of the treatment developed at the Department of therapeutics and clinical diagnostics with the X-ray radiography of the FSBEI HE Kazanskaya SAVM of a preparation containing succinic acid and an organic phosphorus compound on the dynamics of biochemical blood indices characterizing protein, carbohydrate and fat metabolism in rabbits with experimental toxic induced by tetrachloromethane. To study the hepatoprotective effect of the preparation of rabbits with experimental toxic damage of the liver, they were divided according to the principle of analogs into 3 groups: the first group left untreated, the second group - starting from the 5th day of the experiment, three times every 3 days, intramuscular injection of the developed drug in a dose of 1 ml / animal was administered, the third group the preparation was administered an hour before the toxic effect and simultaneously with tetrachloromethane in a similar manner as in the second group. Preventive therapy of animals with acute hepatitis with the test drug was characterized by a statistically significant improvement in biochemical parameters in comparison with the similar indices of both the untreated group and the group of animals receiving the studied agent after the development of the pathological process.