Nitric oxide and hydrogen sulphide as p38-dependent regulators of XIAP and AVEN genes expression in Jurkat cells
Автор: Tashireva L.A., Starikova E.G., Novitskiy V.V., Vasilyeva O.A., Yakushina V.D., Stepovaya E.A., Beldyagina E.V., Zima A.P., Prokhorenko T.S., Osikhov I.A., Saprina T.V.
Журнал: Сибирский онкологический журнал @siboncoj
Рубрика: Лабораторные и экспериментальные исследования
Статья в выпуске: 5 (53), 2012 года.
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In this paper we investigated p38-dependent mechanisms of gaseous transmitters nitric oxide and hydrogen sulfide influence on XIAP and AVEN genes expression in Jurkat cells. Using the method of real-time PCR, XIAP and AVEN genes expression in cancer Jurkat cells was shown. Donors of gases of nitric oxide and hydrogen sulfide were negative regulators of the XIAP and AVEN gene expression in the cells of T-lymphoblast leukemia. Changes in the expression of above mentioned genes under NO and H2S influence occurred with the involvement of p38 MAP kinase
Xiap, aven, apoptosis, nitric oxide, hydrogen sulfide, p38 map kinase
Короткий адрес: https://sciup.org/14056261
IDR: 14056261
