Ontogenetic peculiarities of the formation of the rostos-sternal complex in alloxanic diabetes mellitus

Автор: Ibragimova L.I., Karshiboeva L.A., Gafforova S.Kh., Kurbonboeva M.O.

Журнал: Экономика и социум @ekonomika-socium

Рубрика: Основной раздел

Статья в выпуске: 12-1 (91), 2021 года.

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Diabetes mellitus, commonly known as diabetes, is a metabolic disease that causes high blood sugar. The morphofunctional active point in the formation of the chest is the sternocostal complex. Changes in the shape and functional structure of the chest affect the functional state of the chest cavity organs.The lack of data on the morphofunctional properties of the sternocostal complex leads to serious shortcomings and errors in the prevention and treatment of injuries and deformities in certain areas. The study was carried out on 42 white laboratory rats weighing 150-200 g. The animals were kept in living conditions according to a standard diet (with food and water). For the study, the animals were divided into 2 groups. The material for the study was the breast components of 7-14-21-30-45 days of age in young rats born to mothers with experimental diabetes. For histological analysis in the study, it was necessary to obtain a sternocostal combination of rats of the experimental group. The results of control and morphological studies of the sternocostal complexes in the offspring of experimental rats in the dynamics of growth of early postnatal ontogenesis showed that maternal alloxan diabetes leads to a change in the mechanism of development of the sternum during pregnancy and lactation of a mother with diabetes.

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Chondrocyte, sternocostal complex, experimental diabetes, rats

Короткий адрес: https://sciup.org/140262403

IDR: 140262403

Список литературы Ontogenetic peculiarities of the formation of the rostos-sternal complex in alloxanic diabetes mellitus

  • Ibrokhimova L.I., Rasulov Kh.A. Influence of alloxan diabetes during pregnancy on the morphological formation of the sterno-costal complex. American Journal of Medicine and Medical Sciences DOI:10.5923/j.ajmms. 2021; 11(12): 847-850
  • Hough F.S. et al. Mechanisms in endocrinology: mechanisms and evaluation of bone fragility in type 1 diabetes mellitus. Eur. J. Endocrinol. 2016; 174: R127-138. DOI: 10.1530/EJE-15-0820.
  • Liao C.C., Lin C.S., Shih C.C., Yeh C.C., Chang Y.C., Lee Y.W. et al. Increased risk of fracture and postfracture adverse events in patients with diabetes: two nationwide population-based retrospective cohort studies. Diabetes Care. 2014; 37: 2246-2252.
  • Jackuliak P., Payer J. Osteoporosis, fractures, and diabetes.Int. J. Endocrinol. 2014; 2014: 820615. DOI: 10.1155/2014/820615.
  • Ibrokhimova LI, Rasulov Kh.A., Structural features of the sternocostal complex of rats in the stages of early postnatal ontogenesis in alloxan diabetes mellitus. -118 p
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