Determination of the optimal dose of the complex agent Z-88

The article is devoted to determining the optimal dose of the complex agent Z-88. The experiments were conducted on young mongrel white rats. It was found that intramuscular injections of the drug at a dose of 5.0 ml/kg of body weight inhibited the growth and development of experimental animals. The best growth and development indicators were established in the second experimental group when using the drug, the share of which was 1/20 of the maximum introduced in the experiment for determining the parameters of acute toxicity. In this group, the average daily weight gain at the end of the experiment was 2.23 g. with 1.67 g. in the control; a relative increase of 95.2 %, for the entire period, the body weight reached 121.0 g., which is 18.3% higher than the control.