Determination of the KI-67 threshold value for predicting lymph nodes involvement in patients with gastric cancer
Автор: Ashimov Е.А., Chichevatov D.А., Radovsky V.V., Kolesnikova Е.А., Klimin S.А., Gamayunov S.V., Zagainov V.Е., Kiselev N.М.
Журнал: Злокачественные опухоли @malignanttumors
Рубрика: Оригинальные исследования
Статья в выпуске: 1 т.14, 2024 года.
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The search for biological markers to assess metastatic involvement of the lymph nodes in gastric cancer is one of the key steps in determining treatment tactics. The role of Ki-67 as a marker of cell proliferation in gastric cancer remains relevant. The aim of our study is to determine the Ki-67 threshold value for predicting the lymph nodes metastases. A retrospective analysis of 154 patients with gastric cancer showed an independent and statistically significant relationship between the depth of tumor invasion T (p = 0.002), the differentiation grade G (p = 0.010), the value of the Ki-67 index (p
Gastric cancer, lymph node metastasis, ki-67 proliferative index, prediction, lymph nodes predictors
Короткий адрес: https://sciup.org/140305805
IDR: 140305805 | DOI: 10.18027/2224-5057-2024-14-1-21-29
