Определение порогового значения индекса KI-67 для прогнозирования метастатического поражения лимфатических узлов при раке желудка
Автор: Ашимов Э.А., Чичеватов Д.А., Радовский В.В., Колесникова Е.А., Климин С.А., Гамаюнов С.В., Загайнов В.Е., Киселев Н.М.
Журнал: Злокачественные опухоли @malignanttumors
Рубрика: Оригинальные исследования
Статья в выпуске: 1 т.14, 2024 года.
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Поиск биологических маркеров для оценки метастатического поражения лимфатических узлов при раке желудка - одно из ключевых направлений в определении тактики лечения. Роль индекса Ki-67 как маркера клеточной пролиферации при раке желудка остается актуальной. Целью нашего исследования является определение порогового значения индекса Ki-67 при локализованном раке желудка для прогнозирования метастатического поражения лимфатических узлов. Ретроспективный анализ данных 154 больных раком желудка показал независимую и статистически значимую связь глубины инвазии опухоли T (p = 0,002), степени дифференцировки G (p = 0,010), значения индекса Ki-67 (p
Рак желудка, метастатическое поражение лимфатических узлов, пролиферативный индекс ki-67, прогнозирование, предикторы лимфатического поражения
Короткий адрес: https://sciup.org/140305805
IDR: 140305805 | DOI: 10.18027/2224-5057-2024-14-1-21-29
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