Optimization of the tactics of management of newborns with physiological and neonatal hyperbilirubinemia

Hyperbilirubinemia of the newborn is a common clinical problem that occurs in the neonatal period, especially in the first week of life. Nearly 27% of newborns develop hyperbilirubinemia. According to the National Neonatal-Perinatal Database (NNPD), the incidence of hyperbilirubinemia in newborns in maternity hospitals is 33%, which is a cause for concern for neonatologists and parents of sick children. Hyperbilirubinemia of newborns is dangerous for the development of nuclear jaundice (hyperbilirubin encephalopathy), due to the fact that unconjugated bilirubin freely passes through the blood-brain barrier, leading to the destruction of nerve cells, which leads to the development of neurological disorders in the newborn and form irreversible complications in the form of infantile paralysis . Therefore, the timely detection and treatment of neonatal hyperbilirubinemia is very important, and requires careful monitoring and appropriate preparation.