Main markers of vascular endothelium dysfunction in primary open-angle glaucoma

The review presents current literature data on the functions of the vascular endothelium, its role in the pathogenesis of vascular pathologies, as well as the main markers of its dysfunction. Vascular endothelium plays a role in the development of thrombosis, angiogenesis, remodeling of the vascular wall. It is involved in the regulation of vascular tone, local hemostasis, proliferation. The results of clinical studies of the endothelium capacity, which disorders may accompany primary open-angle glaucoma and contribute to the progression of glaucomatous optic neuropathy, are presented here.