The details of liver function in patients with closed fractures of the lower limb, combined with craniocerebral injury

The details of liver function in patients with closed fractures of the lower limb, combined with craniocerebral injury (CCI), are discussed in the conditions of performing the treatment by transosseous osteosynthesis method. The quick dynamics of protein fraction normal amount recovery was demonstrated in the patients with CCI-free fractures of the lower limbs. By the period of 10 weeks after injury and surgery the values of α2- and β-globulins remained raised, while in patients with CCI the increase of α1-globulins was noted as well. The most significant changes of liver function were observed in patients in the period of 5 weeks after surgery, and in this case the combined injury was accompanied by more marked decrease of urea biosynthesis.