Characteristics of endocrine component of pancreas after administration of N-acetylcysteine in the model of acute radiation-induced pancreatitis

Studies of radiation-induced pancreatic lesions after irradiation with charged particles (electrons, protons) are rare. The effectiveness of certain antioxidants to reduce pancreatic radiation-induced damage is proved. However, the mechanisms of radiation-induced pancreatic damage have not been fully disclosed, and studies of its endocrine component after electron irradiation are rare. The aim of the paper is to assess insulin and glucagon expression in pancreatic islets after administration of N-acetylcysteine in the model of acute post-radiation pancreatitis.