Clinical features of psoriasis in patients with chronic viral hepatitis and HIV infection

Psoriasis is a chronic dermatosis which manifests itself as benign hyperproliferation of epithelial cells with disrupted differentiation and keratinization. In dermatology polymorbidity is quite widespread and relevant, but at the same time it is not sufficiently studied. Psoriasis in patients with HIV infection is often very severe and poorly amenable to standard methods of therapy, which makes study of clinical and immunological specifics of psoriasis natural history in such patients relevant. The disease significantly worsens quality of life, leads to disability and impairs social life of patients. The paper presents a clinical case in which altered clinical presentation and aggressiveness of psoriasis are related to comorbidities, which requires interdisciplinary therapeutic and diagnostic approach.