Peculiarities of peripheral zone pathogenesis in brain oligodendroglioma

Glial brain tumors, unlike other brain tumors, often have a more extensive zone of perifocal edema around the tumor node. The features of the peripheral edema zone depend on the histogenesis and pathogenesis of tumor tissue. We often observe a vast zone of perifocal edema at relatively small tumor sizes and vice versa, a minor zone of perifocal edema at relatively large brain tumor sizes. This proves that the size of the peripheral edema zone is independent of the size of the brain tumor. The expansiveness of the peripheral edema zone in glial tumors of the brain is explained by the fact that glial tumors have rapid reorganized and invasive growth, accompanied by two types of edema (vasogenic and cytotoxic), the presence of pronounced vascular convolutes and toxic effects on healthy brain cells by the decay products of tumor cells. In many cases, the cause of dislocation and hypertension syndrome is often not the tumor itself, but its peripheral edema zone, leading to irreversible processes. Multiple morphological, vascular, water-electrolyte changes in the peripheral edema zone, before and postoperative complications associated with the peripheral edema zone, are of interest to experts. The perifocal edema zone is important in deciding the extent of surgery. The peripheral edema zone is the buffer zone between the tumor and healthy brain tissue. At the same time, decaying apoptotic brain tissues are the object of intoxication and subsequent gliosis sites are the cause of epileptic attacks.