Features of the regeneration of the mucous membrane of the ileum of children with different course of Crohn's disease

Objective: to study features of recovery with the intestine in different currents of Crohn’s disease in children. Materials / patients: in 23 patients with Crohn’s disease in age from 3 to 18 years retrospectively applied a complex morphological study of the mucous membrane of the ileum. Results: in a complicated course of Crohn’s disease mucous membrane of the ileum revealed deeper manifestation of the inflammatory process, compounded by a sharp decline in cells capable of active synthesis of extracellular matrix components. Conclusion: an unfavorable course of the disease the regeneration takes place with the maximum violation of postmitotic cell differentiation.