Real-World Therapeutic Monitoring After Elective Total Knee and Hip Arthroplasty: Single-Center Prospective Cohort Study

Background. The condition of patients after orthopedic surgery requires therapeutic monitoring with correction of concomitant therapy.Aim: To study changes of the general condition of patients after elective total knee arthroplasty (TKA) and elective total hip arthroplasty (THA) over time through active therapeutic monitoring to optimize management.Materials and Methods. This prospective cohort single-center study included 782 patients with detailed medical history, information about concomitant diseases and drug therapy. The severity of pain was assessed on a 10-point scale before surgery and then 1 and 3 months after arthroplasty.Results. The study population included 271 males (34.7%) and 511 females (65.3%). 595 subjects (76.1%) had hypertension (grade 1 - 71 patients, grade 2 - 252 patients, grade 3 - 272 patients). At 1 month after surgery, 18 patients (2.3%) reported instable blood pressure (BP), 43 patients (5.5%) reported a persistent BP decrease requiring a reduction of antihypertensive drugs doses. Before surgery 604 patients (77.2%) were taking non-steroidal anti-inflammatory drugs (NSAIDs); at 1 month a significant (p function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }