Acute kidney injury: new aspects of the well-known problem

Acute kidney injury (AKI), being a frequent condition in patients at ICU, is associated with both significant treatment time and high mortality. However, renal replacement therapy alone is not able to improve the results of treatment of AKI. The present review highlights a number of rarely discussed issues relating to violations of the electrolyte balance and the immune system, nutritional support features, pathophysiology of abdominal compartment-syndrome and Doppler capabilities in the context of an integrated approach to AKI treatment.