Acute kidney injury in patients with ST-segment elevation acute myocardial infarction when using different thrombolytic agents

The purpose of this study was to examine the incidence of the acute kidney injury (AKI), defined by the KDIGO Clinical Practice Guideline in patients with ST-segment elevation acute myocardial infarction, undergoing pharmacological reperfusion different thrombolytic agents. According to KDIGO criteria, 25 % patients had AKI detected by basal serum creatinine. When used to reperfusion streptokinase have a higher frequency and severity of AKI compared with alteplase. This is probably due to the development of hypotension with administration of streptokinase. In patients with ST-segment elevation acute myocardial infarction, severe AKI associated with a poor prognosis.