Acute coronary syndrome and anemia: features of choosing the optimal medical tactics (review)

The review evaluates, according to the literature, the clinical and pathogenetic significance of anemia in patients with acute coronary syndrome (ACS). In this clinical situation, the problems of choosing the optimal therapy associated with the smallest evidence base are highlighted. For this, the results of clinical studies published in bibliographic databases: PubMed, Publons and eLibrary were analyzed (the review included 40 publications for 1989–2020). The epidemiological features of the anemia syndrome in patients with ACS are most well studied. Anemia is often circulated in ACS and is associated with an unfavorable prognosis. The question remains whether anemia plays a direct causal role in the deterioration of short- and long-term morbidity and mortality, or is it rather an indicator of a poor clinical condition. A separate study for ACS in patients with anemia, due to the minimal evidence base, requires the choice of optimal antithrombotic therapy: specific drugs and the duration of their administration