Long-term results of efficacy and safety of pulmonary vein isolation with a catheter-tissue pressure sensor and a second-generation cryoballon in patients with persistent atrial fibrillation

Objective: to conduct a comparative assessment of the annual efficacy and safety of pulmonary vein (PVs) isolation with a catheter with a catheter-tissue pressure sensor and a second-generation cryoballon in patients with persistent atrial fibrillation (AF). To assess the dynamics of quality of life indicators for patients of both groups based on the AFEQT questionnaire Materials and methods: a randomized prospective, single-center study was conducted. The study involved only 70 patients with a persistent form of AF who were randomized into two groups: group 1 (n = 35) - primary isolation of PVs by radiofrequency ablation using a catheter with a catheter-tissue pressure sensor. Group 2 (n = 35) - primary isolation of PVs with a second-generation cryoballon. The observation period was 12 months. A recurrence of atrial fibrillation was considered to be any paroxysm of atrial tachyarrhythmia, lasting more than 30 seconds, arising after the expiration of the “blind period” of the study. In both groups, the dynamics of indicators of the quality of life of patients was calculated based on the AFEQT questionnaire. Results: acute isolation of PVs in the radiofrequency ablation group (RF) was achieved in 100% of PVs, in the cryoballon ablation group (CB) - 97.8% of PVs. The total duration of the procedure (125.3±6.8 versus 93.4±7.3 minutes, p = function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }