Parasitic abscess as an incidental histological finding in the treatment of sigmoid colon cancer
Автор: Galliamov E.A., Agapov M.A., Malkov P.G., Markaryan D.R., Danilova N.V., Kakotkin V.V., Kazachenko E.A., Lukyanov A.M., Oleynikova N.A., Kubyshkin V.A.
Журнал: Хирургическая практика @spractice
Рубрика: Статьи
Статья в выпуске: 3 (43), 2020 года.
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Background: A high worldwide incidence of colorectal cancer defines the importance of search not only for effective treatment methods, but also for risk factors for the cancer development and its worst prognosis. The influence of many genetic factors, environmental characteristics and lifestyle features has already been proven, and recently the attention of researchers is being focused on the study of microbiota and, in particular, various parasitic intestinal diseases in the context of risk factors for colorectal cancer.Clinical case presentation: we demonstrate an incidental finding of parasitic invasion signs during the pathomorphological examination of the surgical specimen in a patient without an epidemiological history.Conclusion: Further studies are needed not only to confirm and substantiate the role of micro- and macroorganisms inhabiting the intestine in the development of oncological diseases, but also to identify individual links of pathogenesis, pathological pathways and signaling molecules involved in carcinogenesis. Research like this could help broaden knowledge about both the risk factors and predictors of colorectal cancer and the potential sites for targeted therapy.
Parasitic bowel diseases, colorectal cancer, risk factors
Короткий адрес: https://sciup.org/142230044
IDR: 142230044 | DOI: 10.38181/2223-2427-2020-3-53-58