Pathophysiological aspects of change of the affective status at sick of chronic nephritic insufficiency

In work the analysis of the data available in the literature on changes and ways of an estimation of the affective status at sick of chronic nephritic insufficiency (ХПН), being on a hemodialysis is carried out. Key mechanisms of change of the affective status at chronic nephritic insufficiency are connected with development nitroemya, level increase paratireoid a hormone in blood, change of balance of electrolits, an exchange of vitamins, a hypoxemia of nervous system, features of therapeutic actions, including a program hemodialysis, a social microenvironment, etc. factors. The special mediko-social importance depressive infringements at patients of chronic nephritic insufficiency represent, lives influencing quality, survival rate and frequency of suicides. The wide spectrum of used methods for monitoring of the affective status doesn't consider feature of a nosology and therapeutic actions at patients of chronic nephritic insufficiency.