Pathogenetic and clinical significance of EPCAM expression features in tumors and circulating tumor cells
Автор: Perelmuter V.M., Tashireva L.A., Grigoryeva E.S., Alifanov V.V., Pudova E.S., Buzenkova A.V., Zavyalova M.V., Cherdyntseva N.V.
Журнал: Сибирский онкологический журнал @siboncoj
Рубрика: Обзоры
Статья в выпуске: 5 т.23, 2024 года.
Бесплатный доступ
Purpose of the study: to summarize the available data on the structure and function of EpCAM and its domains, their roles in promoting proliferation and epithelial-mesenchymal transition (EMT), contributing to cell stemness, and facilitating interactions with cell adhesion and invasion molecules. Material and Methods. A comprehensive search was conducted for articles in Russian and English within the scientific databases PubMed, Scopus, Web of Science, and E-library. A total of seventy-nine articles ranging from 1996 to 2024 were utilized to compile this review.
Epcam, epcamhigh/low/loss, circulating tumor cells, epithelial-mesenchymal transition, carcinomas, breast cancer, invasion, stemness
Короткий адрес: https://sciup.org/140307912
IDR: 140307912 | DOI: 10.21294/1814-4861-2024-23-5-133-145
