The vitreoretinal interface pathology and anti-VEGF therapy of macular edema in diabetic angioretinopathy

The purpose of the study is to assess the effect of vitreoretinal interface changes in patients with diabetic macular edema as far as the effectiveness of anti-VEGF therapy is concerned. Material and Methods. The study included 198 patients (198 eyes) with diabetic macular edema (DME). Two groups were formed: group 1 - patients without pathological changes in vitreoretinal interface (VRI); group 2 - patients with pathological changes in VRI. We studied the best-corrected visual acuity according to the Snellen table, central retinal thickness and VRI condition according to optical coherence tomography before the intravitreal administration and 1 month after. Results. Significant differences in best-corrected visual acuity were observed before and 1 month after intravitreal administration in both groups (p