Prospects for initial triple antihypertensive therapy

The currently recommended initial dual antihypertensive therapy (AHT) results in poor blood pressure (BP) control, whereas most patients should undergo triple-combination therapy to achieve target levels. We have found only foreign publications concerning initial triple antihypertensive treatment. The aim of the study is to compare the traditional step by step strategy of drug administration and application of three antihypertensive drugs simultaneously. Materials and Methods. Trial subjects were divided into 2 groups: patients who received conventional dual therapy followed by a third drug agent (n=59) and patients who received initial triple AHT (n=57). The frequency of prescribed drugs and their dosage were comparable. The examination was carried at hospital according to the current standards of medical care for hypertensive adults. Values