Prospects for herpes simplex vaccine prevention

Recurrent genital herpes is characterized by suppressed cell-mediated reactions as well as interferon and cytokine production. A role of HSV-1 and HSV-2 in affecting severity score and clinical manifestations was examined in 58 young adult female patients. Compared to HSV-1 infection, HSV-2 was found to signiicantly increase intoxication rate, resulting in larger lesion areas, with longer disease duration and higher recurrence rate during a one-year follow-up.Vitaherpavac vaccine targeting herpes simplex viruses was proved to be highly eficient for therapy and prevention by lowering recurrence rate in genital herpes patients as well as prolonging relapse-free interval in 85% female patients, additionally promoting Тh1-dependent immune response (immunorehabilitation)